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A variety of media, supplemental media components, and reagents suitable for cell culture operations and processes. Products include fully prepared media as well as antibiotics, growth factors, contamination detection and removal reagents, cell dissociation reagents, and more.
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Premade antibiotic solutions are ready-to-use as a supplement for your tissue culture, bacteria media or other specific needs. Antibiotics are often used in cell culture to prevent contamination, maintain aseptic conditions, or select for cells containing genetic modifications.
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TPEN (TPEDA) is a specific cell-permeable heavy metal chelator that induces apoptosis in NB4 cells via negatively regulating intracellular NO and Zn2+ signaling. TPEN (TPEDA) may be a potential therapeutic strategy for APL (acute promyelocytic leukemia).TPEN induces DNA damage and increases intracellular ROS production and also inhibits cell proliferation.
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Teglicar is a selective and reversible orally active liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1) inhibitor with an IC50 value of 0.68 μM and a Ki value of 0.36 μM. Teglicar has a potential antihyperglycemic property. It can be used for the research of diabetes and neurodegenerative disease including Huntington's disease (HD).
Selective and reversible orally active liver isoform of carnitine palmitoyl-transferase 1 (L-CPT1) inhibitor.
Has an IC50 value of 0.68 μM and a Ki value of 0.36 μM for L-CPT1.
Possesses potential antihyperglycemic properties.
Suitable for research on diabetes and neurodegenerative diseases, such as Huntington's disease (HD).
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JH-X-119-01 is a potent, selective small-molecule inhibitor of interleukin-1 receptor-associated kinase 1 (IRAK1) with an in vitro IC50 of 9 nM. It is supplied for research use as a powder or as a 10 mM solution in DMSO, with a reported purity of 99.03% and molecular weight of 452.46 g/mol.
Potent IRAK1 inhibition (IC50 9 nM).
High reported purity (99.03%).
Molecular weight 452.46 g/mol.
Available as powder and as 10 mM DMSO solution.
Multiple packaging sizes from milligram to gram scale.
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ROR1 protein s minimal kinase activity in vitro suggests an improbable role as a tyrosine kinase in vivo It serves as a receptor for WNT5A activating NFkB signaling and potentially inhibiting WNT3A signaling Notably ROR1 plays a vital role in the inner ear facilitating innervation of auditory hair cells by spiral ganglion neurons ROR1 Protein Human (sf9 His) is the recombinant human-derived ROR1 protein expressed by Sf9 insect cells with C-His labeled tag
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RSPO1/R-spondin-1 is a secreted glycoprotein RSPO1/R-spondin-1 binds to LGR4/5/6 receptors and ZNRF3/E3 ubiquitin ligases inhibits Wnt receptor degradation stabilizes -catenin and promotes its nuclear translocation and activates target gene transcription RSPO1/R-spondin-1 Human promotes intestinal organoid survival induces pancreatic -cell proliferation to improve diabetes enhances osteogenic differentiation of mesenchymal stem cells to treat osteoporosis and inhibits bone erosion in arthritis models RSPO1/R-spondin-1 Protein Human (HEK293 His) is a recombinant RSPO1/R-spondin-1 protein expressed by HEK293 with a C-His tag
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PDGF-DD Protein Human (CHO) is a member of the PDGF family specifically binds to and activates its cognate receptor PDGFR- and participates in regulating cancer proliferation transformation and invasion through activating multiple downstream oncogenic pathways resulting in tumor development and progression
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CD4 Protein is expressed on the surface of helper T cells It plays a key role in immune responses by binding to major histocompatibility complex class II molecules on antigen-presenting cells facilitating T cell activation and cytokine production CD4 Protein is also involved in immune regulation and tolerance Understanding its functions can aid in developing therapies for autoimmune diseases and immunodeficiencies CD4 Protein Rat (HEK293 His) is the recombinant rat-derived CD4 protein expressed by HEK293 with C-His labeled tag
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FGF-13 protein is a microtubule-binding protein that directly binds and stabilizes tubulin and affects microtubule polymerization It exerts negative regulation on axonal and leading process branches which are critical for neuronal polarization and migration in the cerebral cortex and hippocampus FGF-13 Protein Human is the recombinant human-derived FGF-13 protein expressed by E coli with tag free
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